Seed cycling is an alternative medicine practice believed to help regulate reproductive hormones.
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Data is de-identified
Your data is stripped of direct identifiers and handled according to strict privacy and security standards. You can read more about how Clue handles your data in our Privacy Policy.
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Researchers use this data for real-world impact
This becomes part of a unique dataset used by top research institutions and clinicians to provide the scientific evidence base for women’s health, explore real-world impact, understand diversity, and break taboos.
Our criteria for partnerships
We collaborate with carefully chosen research partners on studies that meet high scientific, ethical, and data protection standards.
Every study we support must:
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Answer clear scientific questions relevant to menstrual and reproductive health.
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Meet high standards of scientific quality and ethical review.
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Adhere to strict GDPR-compliant data protection standards
Meet the women powering Clue’s science
Behind every data point, research study, and evidence-based insight.
Trained in molecular biology, Amanda began her career in ovarian cancer research before moving into digital health. As fractional Chief Science Officer at Clue, she leads scientific research and global collaborations leveraging real-world menstrual and reproductive health data to accelerate discovery and help close the women’s health knowledge gap.
Kirsten has a PhD in cognitive neuroscience. After analyzing large-scale datasets in academia, she now analyzes Clue’s user data for insights, works on AI features that give users menstrual health-related insights, and supports important research collaborations.
With a PhD in reproductive biology, Cornelia leads Clue’s science team to ensure all features and content are grounded in science. Her team conducts research to advance women’s health, and creates educational content that helps people make informed health decisions.
With a background as a medical doctor, Hajni worked in various roles business and scientific roles across industry, in startups and in pharmaceuticals.Hajni bridges the gap between clinical research and real-world evidence. She leads Clue’s strategic partnerships with life science institutions and researchers, leveraging Clue’s unique dataset to accelerate breakthroughs in female health and close the gender data gap on a global scale.
Board-certified OB-GYN and specialty-certified Pediatric & Adolescent Gynecologist. Known as 'The Period Doctor' on social media, she sets the record straight on female health topics through no-nonsense educational content and myth busting.
Eve is a fertility nurse by training and a reproductive health advisor at Clue. She works on product features supporting menstrual and reproductive health, drawing on clinical experience and evidence-based science.
How do menstrual cycle hormones influence women’s vulnerability to PTSD?
A controlled clinical study tested how the hormone estradiol shapes the brain’s response to threat and stress. The results suggest hormonal changes across the menstrual cycle may influence PTSD vulnerability.
Did the COVID-19 pandemic impact menstrual cycles?
While there has been anecdotal evidence from people experiencing menstrual cycle changes (such as longer cycles or heavier periods) after COVID-19 infection or vaccination, there have been few studies on the topic.
How do different people experience heavy menstrual bleeding?
This project compared Clue users’ tracked bleeding with their responses to an online questionnaire and found that for people who reported having a heavy period, actual flow heaviness was not always the most important factor in characterizing their period.
Can air pollution affect the menstrual cycle?
Analyzing over 2.2 million cycles from 92,000 Clue users in 230 cities across the U.S., Brazil, and Mexico, this study found that higher long-term exposure to a certain type of air pollutant (PM2.5) was associated with increased cycle irregularity, particularly longer cycles.
Are digestive symptoms associated with mood during PMS?
This study examined how digestive symptoms vary across the menstrual cycle and relate to mood, finding a strong link between the digestive and mood symptoms, especially among people with PMS.
What is the contribution of menstrual cycles to mood, behavior, and vital signs?
Using machine learning on millions of cycles, this study found menstrual cycles influence mood and behavior more strongly than daily, weekly, or seasonal cycles.
How do menstrual cycle lengths and symptoms vary — and can AI help us more accurately predict when an individual’s next period will be?
This research explored cycle variability and symptom patterns, and developed AI models to improve period prediction by accounting for potential missed tracking.
Do STIs influence premenstrual symptoms?
This study found that undiagnosed STIs were associated with increased pain and low mood before menstruation, suggesting symptoms may signal underlying conditions.
How does sexual desire change across the menstrual cycle and with contraceptive use?
This research examines how sexual desire changes across the menstrual cycle and under different contraceptive methods, helping to clarify potential side effects and cycle-related patterns.
What do menstrual cycle patterns look like in adolescents, and how are they shaped by stress and physical activity?
This research explores how adolescent menstrual cycles vary after menarche, and how factors like stress and physical activity influence cycle characteristics.
What symptom patterns are experienced during perimenopause?
This study examines the wide range of perimenopause symptoms, from hot flashes to sleep disturbances, to better understand how they vary across individuals and over time.
Can self-tracked menstrual patterns be used to detect endometriosis?
Machine learning applied to tracked menstrual data may help detect endometriosis earlier by identifying characteristic symptom patterns.
Do focus, attention, and motivation change across the menstrual cycle among those with and without ADHD?
This research explores how menstrual cycles affect focus, motivation, and mental functioning in people with and without ADHD.
Can menstrual cycle tracking help improve the diagnostic criteria for PMDD?
This study is mapping symptom patterns in PMDD in an effort to refine diagnostic criteria and support more effective screening and treatment.
How does the menstrual cycle impact mood and energy in people with or without health conditions?
This research explores cycle-related changes in mood and energy, comparing individuals with and without health conditions like depression and anxiety.
Is there an association between menstrual patterns and breast cancer risk?
This study investigates links between menstrual cycle characteristics and breast cancer risk, aiming to identify early warning patterns.
Are there recurring patterns to menstrual pain, and how are they influenced by reproductive health conditions?
This research examines recurring period pain patterns and how underlying reproductive conditions influence symptom severity and experience.
Do patterns in sexual activity or fertility shape birth seasonality?
This study assesses whether seasonal birth trends may be influenced by patterns in sexual activity or fertility.
How well can menstrual tracking apps predict pregnancy?
This research evaluates how app-tracked cycle and sexual activity data can predict pregnancy likelihood.
How does menses impact attitudes and behaviors around condom use?
This study examines how menstrual bleeding influences attitudes and behaviors around condom use worldwide.
How do menstrual bleeding preferences impact contraceptive decision-making?
This research explores how preferences for menstrual bleeding influence birth control choices across cultures.
How do people use mobile technology for sex-related purposes?
This study investigated how people use mobile technology for sexual health, partner connection, and education globally.
What are people looking for in an ideal romantic partner?
This study examines global preferences for romantic partners, exploring how age and cultural factors influence desires.
How can menstrual tracking apps support reproductive health research?
We need more effective ways to quickly and inexpensively collect health data—could apps like Clue be a solution?
How you can help
Historically, women and people with periods have been underrepresented in research. Your involvement with Clue can help change that.
Here’s how you can get involved:
Contribute your tracked data
Give consent in your Clue app’s privacy settings to share your de-identified data, helping researchers answer important questions about menstrual and reproductive health.
Take part in Clue surveys
Occasionally, you may be invited to take part in a survey. Surveys can be anonymous or linked to your de-identified data. You’ll always see an introduction explaining what data will be used.
Participate in a clinical study
Researchers can use Clue to collect cycle data for studies, such as investigating how exercise impacts menstrual bleeding. Keep an eye on invitations to clinical research.
Join studies promoted by Clue
We help researchers recruit participants from diverse backgrounds. You might see studies promoted in-app or on our social channels that you can take part in.
If you’re a researcher interested in collaborating with Clue, we’d love to hear from you.
